At Loyal we’re developing the first FDA-approved drugs explicitly intended to extend lifespan and healthspan, and being first means charting new waters.
On the path to FDA approval, we must run a clinical trial that objectively and robustly demonstrates that our drug extends dogs’ healthy lifespan, and does so safely. Because no one has developed a dog — or human — longevity drug before, we are building the path to FDA approval largely from scratch.
Last week we learned from the FDA that Loyal received protocol concurrence for our companion dog longevity study — likely the first time the FDA has given their blessing to a longevity clinical trial. Our regulatory expert Karen Greenwood weighs in on what this means for Loyal, for the field of aging, and for dogs everywhere.
Dr. Brennen McKenzie often teaches continuing education courses around canine aging, and he shares resources that include foundational material on aging, clinical assessment tools, and guidelines to assist vets in creating treatment plans for senior dogs.
How are dogs like probiotics? Well, they’re cuter and furrier, but they also change our microbiome and can even reduce our risk of allergies! Let’s investigate how dogs influence our microbiome and our immune systems.
Discussing weight and how it impacts our dog’s health is important to how we think about our dog’s aging and quality of life. Here are practical tips and evidence-based advice to help your dog get to their healthiest weight.
How does movement impact longevity? Can physical activity help my dog live longer? Here’s how exercise maintains good health and slows aging.
Do you ever wonder how your dog might look, feel, or act as they advance in age? Understanding aging gives us the potential to prevent or mitigate a wide range of age-related health problems in dogs.
There are now lots of devices that let us call our dogs and say “Hi!” when we aren’t at home. But are these really for our dogs, or just for us?
Sometimes our dogs seem to read us like an open book! How do they know just how we are feeling? It turns out, our faces are a clear window into our emotions for our canine friends.
Dogs are exceptionally good at understanding humans; better than any animal outside our own species. But when we talk to them, we give a lot of information besides just words.
Humans are not the only animals to yawn. Fish, birds and mammals all yawn too. And, of course, so do our favorite animals here at Loyal!